Indapamide
Indapamide is a diuretic that works on the kidneys to remove excess sodium, potassium, chloride, and fluid from the body in order to reduce blood pressure, swelling (oedema), and the workload on the heart. It is available only by prescription. Possible serious side effects include low sodium and low potassium (electrolyte disturbances), too much fluid loss, and allergic reactions. It may cause gout. Indapamide interacts with a number of medications, so inform your doctor and pharmacist of all other medicines you take. Indapamide has an advantage over most diuretics because it does not increase cholesterol and blood glucose.

Brand Names Available
Chem mart Indapamide, Coversyl Plus, Dapa-Tabs, GenRx Indapamide, Indahexal, Insig, Napamide, Natrilix,Natrilix SR, Terry White Chemists Indapamide
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Available As
Tablets, Slow-Release tablets, Schedule 4 - prescription only product, Generic equivalents are available.
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What is it?
Cardiovascular drug
Drug for high blood pressure, heart failure, and oedema (swelling)
Diuretic
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Main Uses
Diuretics are used in the treatment of high blood pressure, heart failure, and oedema (swelling).
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How does it work?
Indapamide acts on the kidneys to increase the amount of sodium, potassium, chloride, and water excreted in the urine – effectively removing fluid from the body. This reduces blood pressure, oedema, and workload on the heart.
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Dosage and Directions for use
Adults: 1.25-2.5mg daily, usually as a single dose.
May be taken with or without food.
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Possible Side Effects

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Serious
Electrolyte disturbances (low sodium, low potassium). Allergic reactions ranging from mild rash to anaphylaxis.
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Common
Precipitation of gout attacks
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Less Common
Kidney damage. Increased calcium levels. Pancreatitis. Photosensitivity (excessive sensitivity to light). Rare blood changes.
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Precautions
Pregnancy – unsafe.
Breast feeding – not advised (reduces milk production).
Aged – may need lower doses.
Children – not used.
Driving and hazardous work – no specific precautions needed.
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Contra Indications
Kidney disease
Gout
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Overdose
Overdose can cause multiple and severe side effects (see above). Gastric lavage (emptying of stomach) and general supportive treatment is recommended.
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Interaction with other medicines
Many medicines, including this one, have interactions with other medicines and it is wise to inform your doctor and pharmacist of any and all medicines you take.
Seek medical advice if you use corticosteroids (cortisone, prednisone), cholestyramine, or lithium.
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Special Issues
Indapamide does not elevate cholesterol and blood glucose, which is an advantage compared with most diuretics.
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Short Description
Indapamide (e.g. Natrilix, Daptril) is a diuretic that works on the kidneys to remove excess sodium, potassium, chloride, and fluid from the body in order to reduce blood pressure, swelling (oedema), and the workload on the heart.
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Featured Description

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Keywords
indapamide, diuretic, high blood pressure, heart failure, kidneys, sodiuum, potassium, chloride, blood pressure, oedema, natrilix, indalix, daptril, dapamax
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