Cefuroxime
Cefuroxime is a cephalosporin antibiotic used to treat throat, ear, chest, bladder and kidney (urinary tract), skin, and other infections. It is available by prescription only. Common possible side effects include oral or vaginal thrush (Candida infection), inflammation of the colon, nausea, diarrhoea, and heart burn. More serious possible side effects include severe allergic reactions. People who are allergic to penicillins may also be allergic to cephalosporins.

Brand Names Available
Zinnat
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Available As
Tablets, Schedule 4 - prescription only product
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What is it?
Antibiotic
Cephalosporin
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Main Uses
Antibiotics weaken or destroy bacteria (a form of micro-organism) and are thus used to treat infections caused by bacteria. Cefuroxime is used in the treatment of throat, ear, chest, urinary tract (bladder and kidney), skin, and other infections.
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How does it work?
Cephalosporin antibiotics interfere with bacterial cell walls, either destroying or weakening the bacteria.
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Dosage and Directions for use
Oral doses:

Adults: 250-500mg 12 hourly
Children under 12: 125-250mg 12 hourly
Infants (under 1 year): 62.5-125mg 12 hourly
May be taken with or without food.
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Possible Side Effects

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Serious
Allergic reactions from mild rash to fatal anaphylaxis.
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Common
Antibiotics often change the natural balance of organisms within the body, which may lead to overgrowth problems such as candida infection (oral or vaginal thrush) and intestinal problems like psuedomembranous colitis (inflammation of the colon that may cause diarrhoea, abdominal pain and bleeding). Nausea, diarrhoea, abdominal pain and heartburn are fairly common side effects, but are usually not severe.
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Less Common
Kidney damage. Liver damage. Blood changes (reduced red blood cells, white blood cells, and platelets) that may lead to anaemia, increased susceptibility to infection, and bleeding problems.
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Precautions
Pregnancy – safety not established.
Breast feeding – safety not established.
Aged – may need reduced dose.
Children – generally considered safe but not for newborn infants.
Driving and hazardous work – no special precautions needed.
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Contra Indications
Known allergy to cephalosporins or penicillins
Newborn babies
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Overdose
Overdose can cause multiple and severe side effects (see above). If hypoglycaemia occurs then the patient should be hospitalised immediately as this may develop into a potentially fatal coma.
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Interaction with other medicines
Many medicines, including this one, have interactions with other medicines and it is wise to inform your doctor and pharmacist of any and all medicines you take.
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Special Issues
People who are allergic to penicillins may also be allergic to cephalosporins (cross-reactivity) and should not be given cephalosporins.
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Short Description
Cefuroxime (e.g. Zinnat) is a cephalosporin antibiotic used to treat throat, ear, chest, bladder and kidney (urinary tract), skin, and other infections.
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Featured Description

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Keywords
cefuroxime, cephalosporin, antibiotic, zinnat, intracef, cephalosporin antibiotic, infections
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